Update to HCCM mouse analgesia formulary

January 18, 2022

HCCM has recently updated its analgesia formulary for mice. Changes include:

  • Buprenoprhine HCl:
    • Increased frequency of administration from q8-12 hours to q4-6h
  • Bup-SR:
    • Added to the formulary – everyone is encouraged to use this over the non-SR formulation
  • Meloxicam:
    • Increased dose and frequency – previously 5 mg/kg q24h, now 5-10 mg/kg q12-24h
  • Ketoprofen:
    • Increased...
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COVID-19 Update

March 13, 2020

The IACUC staff will make every effort to continue to carry out IACUC functions, but please be aware of the following:

  • IACUC staff is currently working remotely
  • Semiannual inspections may need to be rescheduled
  • IACUC approval on new animal work will be based on the animal care program’s ability to care for the animals

The IACUC staff will update this page as...

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Pain Management in Rodents

February 24, 2020

The December 2019 issue of Comparative Medicine is devoted to pain as a clinical factor and experimental variable in laboratory rodents – covering ethical considerations regarding analgesia and pain management, the importance of pain recognition and management, sex and strain differences in response to pain and analgesics in mice, as well as the impact of pain on different models involving laboratory mice and...

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NSAID Availability Curtailed. Back Order Alert!

October 7, 2019

Please be aware that alternative options for NSAID use in research surgeries may be necessary because of recent shortages of supply of injectable meloxicam and carprofen. These drugs have recently been back-ordered or are in very short supply. As part of surgical planning, investigators using these medications in their research programs should take note of their current stock and match it with their planned usage. Speak with the HCCM veterinary staff if you find yourselves unable to re-order the analgesics approved on your IACUC protocol.

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Webinar on Mouse Anesthesia

January 3, 2019

OOTI and HCCM will be co-sponsoring a webinar presented by AALAS on mouse anesthesia on January 23, 2019 from 1:00-2:30pm at the Snyder Auditorium (Kresge G2). Last presented in September 2017, this webinar covers topics such as surgical plane of anesthesia, multimodal anesthesia, and injectables vs. inhalants.

All are invited to attend.  Location will be announced shortly.

For more information, visit the ...

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New Training Available: Controlled Substances in Research

August 2, 2018

EHS has just introduced a new online training on the use of DEA controlled substances in research. 

This course provides instructions for obtaining, securing, using, and disposing of controlled substances used in research, in accordance with the US Department of Justice, Drug Enforcement Administration, Controlled Substances Act (21 CFR 1300) and Massachusetts Department of Public Health (105 CMR 700).

This course is intended for Researchers, Veterinarians, Principal Investigators, Research Operations Managers, and others involved in the management and use of...

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